[1]杨兵,李晓凤,夏先林.牛膝多糖对断奶仔猪氧化应激和免疫功能的影响[J].江苏农业学报,2017,(03):618-623.[doi:doi:10.3969/j.issn.1000-4440.2017.03.019]
　YANG Bing,LI Xiao-feng,XIA Xian-lin.Oxidative stress and immunity of weaned piglets in response to Achyranthes bidentata polysaccharide[J].,2017,(03):618-623.[doi:doi:10.3969/j.issn.1000-4440.2017.03.019]
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牛膝多糖对断奶仔猪氧化应激和免疫功能的影响()
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江苏农业学报[ISSN:1006-6977/CN:61-1281/TN]

卷:
期数:
2017年03期
页码:
618-623
栏目:
畜牧兽医·水产养殖
出版日期:
2017-06-30

文章信息/Info

Title:
Oxidative stress and immunity of weaned piglets in response to Achyranthes bidentata polysaccharide
作者:
杨兵1; 李晓凤2; 夏先林3
（1.铜仁职业技术学院饲料与动物营养实验室，贵州铜仁554300；2.铜仁职业技术学院护理学院，贵州铜仁554300；3.贵州大学动物科学学院，贵州贵阳550025）
Author(s):
YANG Bing1; LI Xiao-feng2; XIA Xian-lin3
(1.Lab of Feedstuff and Animal Nutrition, Tongren Vocational and Technical College, Tongren 554300, China;2.College of Nursing, Tongren Vocational and Technical College, Tongren 554300, China;3.College of Animal Science and Technology, Guizhou University, Guiyang 550025, China)
关键词:
牛膝多糖; 免疫; 氧化应激; 断奶仔猪
Keywords:
Achyranthes bidentata polysaccharide; immunity; oxidative stress; weaned piglet
分类号:
S816.75
DOI:
doi:10.3969/j.issn.1000-4440.2017.03.019
文献标志码:
A
摘要:
选取体质量和遗传基础相近的25日龄杜长大（DLY）断奶仔猪36头，随机分成对照组和2个试验组，每组3个重复，每个重复4头仔猪（公母比为1∶1）。分别饲喂添加0 mg/kg牛膝多糖（ABPS）（对照组）、600 mg/kg ABPS（试验组1）和1 200 mg/kg ABPS（试验组2）的日粮。血样生化指标测定结果表明：添加牛膝多糖对仔猪血清超氧化物歧化酶（SOD）、过氧化氢酶（CAT）活性无影响（P>005），试验组2的谷胱甘肽过氧化物酶（GSH-Px）活性和总抗氧化能力（T-AOC）显著高于对照与试验组1（P<005）；试验组1的丙二醛（MDA）含量显著低于对照组（P<005），而血清免疫球蛋白IgA浓度显著高于对照（P<005），血清免疫球蛋白IgG浓度显著高于对照和试验组2（P<005）；试验组2的血清免疫球蛋白IgM浓度和血清球蛋白浓度显著高于对照和试验组1（P<005），而白蛋白/球蛋白比例显著低于对照和试验组1（P<005）；试验组1、2的血清总蛋白浓度显著高于对照组（P<005），但血清溶菌酶活性显著低于对照（P<005）。综上，牛膝多糖能够显著改善断奶仔猪氧化应激反应及免疫力，改善仔猪健康状态。
Abstract:
A total of thirty-six 25-day-old DLY weaned piglets with similar genetic background and weight were divided into three groups with three replicates per group and 4 pigs per replicate in a randomized complete block. The control was fed on basal diet, and the other two groups were fed on basal diet supplemented with 600 mg/kg Achyranthes bidentata polysaccharide (ABPS) (group 1) and 1 200 mg/kg ABPS (group 2), respectively. The results showed that ABPS did not affect the activities of superoxyde dismutase (SOD) and catalase (CAT) in serum (P>0.05). Seral glutathion peroxidase (GSH-Px) activities and total antioxidant capacity (T-AOC) of the piglets in group 2 were significantly higher than those in control and group 1 (P<005). The concentrations of malondialdehyde (MDA) in the piglets of group 1 was significantly decreased compared to control (P<005), however, the immunoglobulin A (IgA) concentration was increased(P<005), and serum IgG in group 1 was higher than those in control and group 2 (P<005). Sera IgM globulin concentrations in group 2 was higher than those in control and group 1 (P<005), however, the ratio of albumin to globulin was lower. Total protein in groups 1 and 2 were boosted compared to those in control, but serum lysozyme activity was lowered (P<005). In conclusion, A. bidentata polysaccharide can significantly improve the oxidative stress and immunity, thereby enhancing the state of health in weaned piglets.

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备注/Memo

备注/Memo:
收稿日期：2016-12-30 基金项目：贵州省农业科技基金项目[黔科合NZ(2014)3044]；铜仁市科技计划项目[铜市科研（2016）17号-4] 作者简介：杨兵（1986-），男，安徽安庆人，博士研究生，讲师，研究方向为生物技术与动物育种。(E-mail)bingyang19860919@163.com 通讯作者：夏先林, (E-mail)xiaxl1952@sina.com
更新日期/Last Update: 2017-06-29