[1]杜宜楠,赵泓淙,严传婷,等.雌激素对消化道功能活动调节研究进展[J].江苏农业学报,2019,(06):1501-1505.[doi:doi:10.3969/j.issn.1000-4440.2019.06.032]
　DU Yi-nan,ZHAO Hong-cong,YAN Chuan-ting,et al.Research progress of the regulation of estrogen on the digestive functional activity[J].,2019,(06):1501-1505.[doi:doi:10.3969/j.issn.1000-4440.2019.06.032]
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雌激素对消化道功能活动调节研究进展()
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江苏农业学报[ISSN:1006-6977/CN:61-1281/TN]

卷:
期数:
2019年06期
页码:
1501-1505
栏目:
综述
出版日期:
2019-12-31

文章信息/Info

Title:
Research progress of the regulation of estrogen on the digestive functional activity
作者:
杜宜楠1; 赵泓淙2; 严传婷1; 范卡敏1
(1.陕西师范大学现代教学技术教育部重点实验室，陕西西安710062；2.西北农林科技大学动物医学院，陕西杨凌712100)
Author(s):
DU Yi-nan1; ZHAO Hong-cong2; YAN Chuan-ting1; FAN Ka-min1
(1.Key Laboratory of Modern Teaching Technology, Shaanxi Normal University, Xi’an 710062, China；2.College of Veterinary Medicine, Northwest A&F University, Yangling 712100, China)
关键词:
雌激素; 雌激素受体; 消化道; 运动功能; 分泌功能
Keywords:
estrogen; estrogen receptor; digestive tract; motor function; secretion function
分类号:
R333
DOI:
doi:10.3969/j.issn.1000-4440.2019.06.032
文献标志码:
A
摘要:
雌激素是一类主要由卵巢和睾丸产生并分泌的性类固醇激素，参与消化道很多功能活动的调节过程。雌激素的特异性受体ERα、ERβ和GPER广泛分布在消化道的不同分段中，并且分布特点不同，因此执行的生理功能不同。雌激素对消化道运动功能呈浓度依赖性的双相性调节，对消化道分泌功能的调节主要体现在维持盐酸-碳酸氢盐的分泌平衡，表明雌激素可以维持消化道功能活动的稳定，这将为消化道相关疾病的预防和治疗提供理论依据。
Abstract:
Estrogen is one of the sex steroid hormone produced and secreted mainly by ovaries and testes, which participates in the regulation of many digestive functions. The specific estrogen receptors ERα, ERβ and GPER are all widely distributed in different segments of the digestive tract and present their own characteristics of distribution, thus performing different physiological functions. Estrogen showed concentration dependent diphasic regulation model in the regulation of digestive motility and took part in the regulation of digestive secretion by maintaining the secretion balance between hydrochloric acid and bicarbonate. The above results indicated that estrogen could maintain stability on the functional activity of digestive tract. This will provide a theoretical reference for the prevention and treatment of related digestive tract diseases.

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备注/Memo

备注/Memo:
收稿日期：2019-03-27 作者简介：杜宜楠（1993-），男，山西晋中人，博士研究生，主要从事生理学相关工作。（E-mail）1985402828@qq.com 通讯作者：范卡敏，（E-mail）654556203@qq.com
更新日期/Last Update: 2020-01-09