[1]王孝义,李明丽,严达伟,等.不同留种策略下基因辅助BLUP 的选择效果[J].江苏农业学报,2017,(01):113-118.[doi:10.3969/j.issn.1000-4440.2017.01.018 ]
　WANG Xiao-yi,LI Ming-li,YAN Da-wei,et al.Effects of gene-assisted BLUP under different selection strategies[J].,2017,(01):113-118.[doi:10.3969/j.issn.1000-4440.2017.01.018 ]
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不同留种策略下基因辅助BLUP 的选择效果()
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江苏农业学报[ISSN:1006-6977/CN:61-1281/TN]

卷:
期数:
2017年01期
页码:
113-118
栏目:
畜牧兽医·水产养殖
出版日期:
2017-02-28

文章信息/Info

Title:
Effects of gene-assisted BLUP under different selection strategies
作者:
王孝义; 李明丽; 严达伟; 兰国湘; 董新星; 苟潇; 鲁绍雄
（云南农业大学动物科学技术学院，云南昆明650201）
Author(s):
WANG Xiao-yi; LI Ming-li; YAN Da-wei; LAN Guo-xiang; DONG Xin-xing; GOU Xiao; LU Shao-xiong
（College of Animal Science and Technology, Yunnan Agricultural University, Kunming 650201, China）
关键词:
基因辅助BLUP; 留种策略; 遗传进展; 近交系数; QTL增效等位基因
Keywords:
gene-assisted BLUP; selection strategy; genetic response; inbreeding coefficient; QTL favorable allelegene-assisted BLUP; selection strategy; genetic response; inbreeding coefficient; QTL favorable allelegene-assisted BLUP; selection strategy; genetic response; inbr
分类号:
S813.2
DOI:
10.3969/j.issn.1000-4440.2017.01.018
文献标志码:
A
摘要:
为揭示基因辅助最佳线性无偏预测（BLUP）方法在不同留种策略下的选择效果，在假定目标数量性状同时受1个双等位基因QTL和多基因共同控制的前提下，模拟了在一个闭锁群体（10头公畜、190头母畜）内采用标记辅助BLUP连续选择10代的情形。选择试验共考虑了3种留种策略：策略Ⅰ仅根据个体估计育种值（EBV）高低留种；策略Ⅱ在每个公畜家系内选留EBV最高的1头公畜和19头母畜；策略Ⅲ在每个公畜家系内选留1头EBV最高的公畜，在每个母畜家系内选留EBV最高的1头母畜。结果表明，留种策略Ⅰ的遗传进展（包括QTL基因型值和多基因育种值进展）最高，QTL增效等位基因频率上升速度最快，其次为策略Ⅱ，策略Ⅲ的遗传进展最低，QTL增效等位基因频率上升最慢；不同留种策略下的群体近交系数总体上呈现策略Ⅰ>策略Ⅱ>策略Ⅲ的规律，但策略Ⅱ的群体近交系数与策略Ⅲ接近且远低于策略Ⅰ。在育种实践中实施基因辅助BLUP选择时，策略Ⅱ既能保证较高的遗传进展，又能有效控制近交，因而不失为一种理想的留种策略。
Abstract:
In order to reveal the effects of gene-assisted best linear unbiased prediction (GBLUP) under different selection strategies, a continuous 10 generations selection experiment was simulated in a closed population consisting of 10 sires and 190 dams by using GBLUP, assuming that the target quantitative trait was controlled by one bi-allelic quantitative traits locus (QTL) and polygenes. In the experiment, three selection strategies were involved, select breeders only according to the estimated breeding value (EBV) of candidates (i.e. strategy Ⅰ), select the highest EBV of one male and 19 female breeders from each sire family (i.e. strategy Ⅱ) and select the highest EBV of one male from each sire family and the highest EBV of one female breeder from each dam family (i.e. strategy Ⅲ). The results indicated that the highest genetic response (include QTL and polygene effects) and the fastest rise of frequency of QTL favorable allele would be gained by strategy Ⅰ, followed by strategy Ⅱ, and the lowest genetic response and the slowest rise of frequency of QTL favorable allele would be gained by strategy Ⅲ; a tendency of strategy Ⅰ＞strategy Ⅱ＞strategy Ⅲ was also showed on population inbreeding coefficients, but the inbreeding levels of strategy Ⅱ and Ⅲ were much closer and far lower than that of strategy Ⅰ. The strategy Ⅱ could not only gain higher genetic response, but also control the inbreeding effectively, which was an effective selection strategy, when GBLUP selection was implemented in practical breeding.

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期：2016-04-08 基金项目：云南省高校科技创新团队支持计划项目[云教科(2014)22号]；云南省重大科技专项（2012ZA018）；云南省现代农业生猪产业技术体系建设项目（2016KJTX007）；云南农业大学研究生科技创新项目（2015ykc8） 作者简介：王孝义（1986-），男，河南固始人，博士研究生，主要从事分子数量遗传与动物育种研究。(E-mail) wangxiaoyi0101@126.com 通讯作者：鲁绍雄，(Tel) 0871-65220375；(E-mail) shxlu@263.net
更新日期/Last Update: 2017-04-12