[1]华利忠,刘剑锋,冯志新,等.猪伪狂犬病病毒新流行变异毒株的研究进展[J].江苏农业学报,2017,(02):476-480.[doi:doi:10.3969/j.issn.1000-4440.2017.02.037]
　HUA Li-zhong,LIU Jian-feng,FENG Zhi-xin,et al.Progress in novel pseudorabies virus variants prevalent in China[J].,2017,(02):476-480.[doi:doi:10.3969/j.issn.1000-4440.2017.02.037]
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猪伪狂犬病病毒新流行变异毒株的研究进展()
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江苏农业学报[ISSN:1006-6977/CN:61-1281/TN]

卷:
期数:
2017年02期
页码:
476-480
栏目:
综述
出版日期:
2017-04-30

文章信息/Info

Title:
Progress in novel pseudorabies virus variants prevalent in China
作者:
华利忠1; 刘剑锋2; 冯志新1; 杨若松1; 邵国青1
（1. 江苏省农业科学院兽医研究所/农业部兽用生物制品工程技术重点实验室/国家兽用生物制品工程技术研究中心，江苏南京210014;2.南京农业大学，江苏南京210014）
Author(s):
HUA Li-zhong1; LIU Jian-feng2; FENG Zhi-xin1; YANG Ruo-song1; SHAO Guo-qing1
(1. Institute of Veterinary Medicine, Jiangsu Academy of Agricultural Sciences/Key Laboratory of Veterinary Biological Engineering and Technology，Ministry of Agriculture/National Center for Engineering Research of Veterinary Bio-products, Nanjing 210014，China；2. Nanjing Agricultural University, Nanjing 210014，China)
关键词:
猪伪狂犬病毒; 变异株; 分子生物学; 疫苗
Keywords:
pseudorabies virus; variant strain; molecular biology; vaccine
分类号:
S852.65
DOI:
doi:10.3969/j.issn.1000-4440.2017.02.037
文献标志码:
A
摘要:
近30年内，猪伪狂犬活疫苗的应用对中国猪伪狂犬病的防控贡献巨大。2011年以来，中国许多免疫猪场相继暴发猪伪狂犬疫情，给养猪业造成了巨大的损失。研究显示最新流行的PRV毒株为变异株，部分商品化活疫苗不能对其提供完全的保护。本文详细介绍了2011年以来中国猪伪狂犬病的发病情况及其分子流行病学调查结果，分析了猪伪狂犬新变异株的分子生物学特性及其变异株来源，同时论述了针对PRV突变株新型疫苗的研究进展，最后对深入开展中国猪伪狂犬病控制与净化研究进行了展望。
Abstract:
Attenuated live PRV vaccines have contributed effectively to the control of pseudorabies virus (PRV) during the past 30 years in China. However, at the end of 2011, a severe PRV outbreak took place in many PRV vaccinated pig farms and spread quickly in the pig herds in China and caused great economic losses to the swine industry. In this paper, the epidemiological characteristics of swine pseudorabies and the molecular epidemiology of the disease were introduced since 2011 in China. The molecular characteristics of novel PRV variants were analyzed and the research progress of new vaccine against the novel PRV variants was reviewed. The researches on the control and purification of swine pseudorabies was discussed in China.

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　JIANG Zi-yi,LI Bi,CAI Yao,et al.Multiplex PCR identification of pseudorabies vaccine strains and wild viruses[J].,2018,(02):1307.[doi:doi:10.3969/j.issn.1000-4440.2018.06.015]

备注/Memo

备注/Memo:
收稿日期：2016-01-22 基金项目：江苏省农业科技自主创新基金项目[CX(15)1006] 作者简介：华利忠（1982-）,男，江苏无锡人，博士，副研究员，主要从事猪传染病防控技术研究。 通讯作者：邵国青，（Tel）025-84391973；（E-mail）gqshaonj@163.com。
更新日期/Last Update: 2017-05-02