[1]孙慧祥,韩长志.植物叶绿体基因组密码子偏好性研究进展[J].江苏农业学报,2026,42(08):1690-1698.[doi:doi:10.3969/j.issn.1000-4440.2026.08.018]
 SUN Huixiang,HAN Changzhi.Research progress on codon usage bias in plant chloroplast genomes[J].,2026,42(08):1690-1698.[doi:doi:10.3969/j.issn.1000-4440.2026.08.018]
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植物叶绿体基因组密码子偏好性研究进展()

江苏农业学报[ISSN:1006-6977/CN:61-1281/TN]

卷:
42
期数:
2026年08期
页码:
1690-1698
栏目:
综述
出版日期:
2026-08-31

文章信息/Info

Title:
Research progress on codon usage bias in plant chloroplast genomes
作者:
孙慧祥; 韩长志
(西南林业大学林学院/云南省森林灾害预警与控制重点实验室,云南昆明650224)
Author(s):
SUN Huixiang; HAN Changzhi
(College of Forestry, Southwest Forestry University/Yunnan Key Laboratory of Forest Disaster Early Warning and Control, Kunming 650224, China)
关键词:
植物; 叶绿体; 基因组; 密码子偏好性
Keywords:
plants; chloroplast; genome; codon usage bias
分类号:
S718.46
DOI:
doi:10.3969/j.issn.1000-4440.2026.08.018
文献标志码:
A
摘要:
本文系统综述了植物叶绿体基因组密码子偏好性的研究方法、特征及其驱动因素,并比较122种植物的叶绿体基因组密码子特性。结果表明,木本植物叶绿体基因组密码子多以A/T结尾,而草本植物中的单子叶植物则多以G/C结尾。不同植物在应对生物与非生物胁迫时亦表现出不同的密码子使用模式。此外,不同科属的木本植物叶绿体基因组的GC3、相对同义密码子使用度(RSCU)及基因表达效率也存在明显差异,这主要源于对生境的适应性。本文为基因工程设计与多组学整合中的密码子优化策略提供了理论依据。
Abstract:
This paper systematically reviews the research methods, characteristics and driving factors of codon usage bias in plant chloroplast genomes, and compares the codon characteristics of chloroplast genomes from 122 plant species. The results show that chloroplast genome codons of woody plants mostly end with A/T, while monocotyledonous herbaceous plants tend to have G/C-ending codons. Different plants also exhibit distinct codon usage patterns in response to biotic and abiotic stresses. In addition, woody plants of different families and genera present significant differences in the GC3 content, relative synonymous codon usage (RSCU) and gene expression efficiency of their chloroplast genomes, which are mainly attributed to habitat adaptation. This study provides a theoretical basis for codon optimization strategies in genetic engineering design and multi-omics integration.

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备注/Memo

备注/Memo:
收稿日期:2025-08-16基金项目:西南林业大学林学学科和重点实验室开放基金(LXXK-2025M06);云南省“兴滇英才支持计划”青年人才专项(YNWR-QNBJ-2020-188)作者简介:孙慧祥(1999-),男,云南安宁人,硕士研究生,研究方向为资源利用与植物保护。(E-mail)18184860695@163.com通讯作者:韩长志,(E-mail)hanchangzhi2010@163.com
更新日期/Last Update: 2026-09-16