[1]陶志云,徐文娟,朱春红,等.高邮鸭GH 基因SNP 位点及其与早期体质量的相关性[J].江苏农业学报,2017,(01):146-150.[doi:10.3969/j.issn.1000-4440.2017.01.023 ]
 TAO Zhi-yun,XU Wen-juan,ZHU Chun-hong,et al.Polymorphisms of GH gene and relationship between its genotypes and body weight in Gaoyou duck[J].,2017,(01):146-150.[doi:10.3969/j.issn.1000-4440.2017.01.023 ]
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高邮鸭GH 基因SNP 位点及其与早期体质量的相关性()
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江苏农业学报[ISSN:1006-6977/CN:61-1281/TN]

卷:
期数:
2017年01期
页码:
146-150
栏目:
畜牧兽医·水产养殖
出版日期:
2017-02-28

文章信息/Info

Title:
Polymorphisms of GH gene and relationship between its genotypes and body weight in Gaoyou duck
作者:
陶志云徐文娟朱春红宋卫涛章双杰刘宏祥李慧芳束婧婷
(江苏省家禽科学研究所,江苏扬州225125)
Author(s):
TAO Zhi-yunXU Wen-juanZHU Chun-hongSONG Wei-taoZHANG Shuang-jieLIU Hong-xiangLI Hui-fangSHU Jing-ting
(Jiangsu Institute of Poultry Science, Yangzhou 225125, China)
关键词:
生长激素基因(GH)SNP体质量高邮鸭
Keywords:
growth hormone gene(GH)SNPbody weightGaoyou duck
分类号:
S834.2
DOI:
10.3969/j.issn.1000-4440.2017.01.023
文献标志码:
A
摘要:
生长激素(GH)是一种肽类激素,在促进生长和调节体内物质代谢等方面有重要作用。本试验通过检测GH基因在高邮鸭群体中的多态性,筛选与高邮鸭早期体质量相关的GH基因单核苷酸多态性(SNP)位点。在GH基因的第2外显子上发现1个A→G单核苷酸突变位点,形成AA、AG、GG 3种基因型,多态信息含量为0.235,该突变位点处于哈代-温伯平衡状态。在高邮鸭早期生长发育过程中,GG基因型个体的体质量显著高于AA基因型个体和AG基因型个体。结果表明,GG基因型是体质量增长的优势基因型,可以作为高邮鸭早期选育的一个分子标记。通过加大对GG基因型的选育,可能会达到加快育种进程的目的。
Abstract:
Growth hormone (GH) is a peptide hormone, which plays an important role in promoting growth and modulating the metabolism. The polymorphisms of GH gene were detected, and the correlations between GH gene genotypes and body weight in early development were analyzed in Gaoyou duck. The results showed that one single nucleotide polymorphism (SNP), A→G, was detected in exon 2 of GH gene, which formed AA, AG and GG genotypes. The PIC was 0.235, and the mutation site was in Hardy-Weinberg Equilibrium in Gaoyou duck. The body weight of GG genotype was significantly higher than that of AA and AG genotypes in the early development of Gaoyou duck. The results showed that the GG genotype was a favorable genotype and could be used as a molecular marker for the early selection and breeding of Gaoyou duck. The progress of breeding may be accelerated by increasing the selection and breeding of GG genotype.

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备注/Memo

备注/Memo:
收稿日期:2016-05-06 基金项目:江苏省农业科技自主创新基金项目[CX(15)1010-03];扬州市科技计划项目(YZ2015039) 作者简介:陶志云(1979-),女,安徽凤阳人,博士,助理研究员,主要从事家禽免疫及遗传育种方面的研究。(E-mail)zhiyun2@126.com 通讯作者:李慧芳,(E-mail)lhfxf_002@aliyun.com.cn
更新日期/Last Update: 2017-04-12