[1]胡冬春,徐富强,刘旭,等.昆虫生长阻滞肽研究进展[J].江苏农业学报,2023,(04):1072-1079.[doi:doi:10.3969/j.issn.1000-4440.2023.04.017]
　HU Dong-chun,XU Fu-qiang,LIU Xu,et al.Research progress on insect growth-blocking peptide[J].,2023,(04):1072-1079.[doi:doi:10.3969/j.issn.1000-4440.2023.04.017]
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昆虫生长阻滞肽研究进展()
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江苏农业学报[ISSN:1006-6977/CN:61-1281/TN]

卷:
期数:
2023年04期
页码:
1072-1079
栏目:
综述
出版日期:
2023-08-30

文章信息/Info

Title:
Research progress on insect growth-blocking peptide
作者:
胡冬春; 徐富强; 刘旭; 李树忠; 冯从经
（扬州大学植物保护学院,江苏扬州225009）
Author(s):
HU Dong-chun; XU Fu-qiang; LIU Xu; LI Shu-zhong; FENG Cong-jing
（College of Plant Protection, Yangzhou University，Yangzhou 225009，China）
关键词:
生长阻滞肽; 细胞因子; 生长发育; 免疫反应; 生理平衡
Keywords:
growth-blocking peptide; cytokine; growth and development; immune response; physiological balance
分类号:
Q965
DOI:
doi:10.3969/j.issn.1000-4440.2023.04.017
文献标志码:
A
摘要:
在长期进化中，细胞因子在昆虫的环境适应、生长发育和免疫防御中发挥重要作用。昆虫生长阻滞肽（Growth-blocking peptide, GBP）是一种最初在黏虫(Pseudaletia separata)中发现的细胞因子，能够延缓幼虫化蛹。近年来研究结果陆续证实GBP是一种双重生长调节因子，通过影响胰岛素信号通路以调节昆虫生长发育，调控昆虫的免疫和应激反应，平衡体液免疫和细胞免疫。本文简要综述GBP参与调控昆虫免疫、生长与发育的功能，并对未来相关的研究方向和应用进行了展望，有助于了解GBP的生理功能及昆虫维持机体内稳态的分子机制。
Abstract:
Cytokines have played an important role in environmental adaptation, growth and development, and immune defense in insects over the long evolutionary period. Insect growth-blocking peptide (GBP) is a cytokine originally found in Pseudaletia separata, it can delay pupation of the larvae. Recent studies have verified that GBP is a kind of dual growth regulator, which regulates insect growth and development, insect immune and stress responses, and balances humoral and cellular immunity by affecting insulin signaling pathways. In this article, the functions of GBP involved in regulation of insect immunity, growth and development were reviewed, and the future research direction and application were prospected. The results are helpful for understanding the physiological functions of GBP and revealing the molecular mechanisms of insects to maintain the organism homeostasis.

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备注/Memo

备注/Memo:
收稿日期：2022-11-02 基金项目：国家自然科学基金项目（32072417、32202281）作者简介：胡冬春（2000-），男，江苏靖江人，硕士研究生，研究方向为昆虫生理生化与分子生物学。（E-mail）hudongchunlol@163.com 通讯作者：冯从经，（E-mail）fengcj@yzu.edu.cn
更新日期/Last Update: 2023-09-12