[1]祁杰,奚永兰,叶小梅,等.黑水虻幼虫降解抗生素和黑水虻抗菌肽替代抗生素的研究进展[J].江苏农业学报,2026,42(03):638-648.[doi:doi:10.3969/j.issn.1000-4440.2026.03.022]
　QI Jie,XI Yonglan,YE Xiaomei,et al.Research progress on antibiotic degradation by Hermetia illucens larvae and their antimicrobial peptides as antibiotic alternatives[J].,2026,42(03):638-648.[doi:doi:10.3969/j.issn.1000-4440.2026.03.022]
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黑水虻幼虫降解抗生素和黑水虻抗菌肽替代抗生素的研究进展()

江苏农业学报[ISSN:1006-6977/CN:61-1281/TN]

卷:
42
期数:
2026年03期
页码:
638-648
栏目:
综述
出版日期:
2026-03-31

文章信息/Info

Title:
Research progress on antibiotic degradation by Hermetia illucens larvae and their antimicrobial peptides as antibiotic alternatives
作者:
祁杰1; 2; 奚永兰1; 叶小梅1; 2; 孔祥平1; 杜静1; 王莉1
(1.江苏省农业科学院畜牧研究所/农业农村部种养结合重点实验室,江苏南京210014；2.江苏科技大学生物技术学院,江苏镇江212000)
Author(s):
QI Jie1; 2; XI Yonglan1; YE Xiaomei1; 2; KONG Xiangping1; DU Jing1; WANG Li1
(1.Institute of Animal Science, Jiangsu Academy of Agricultural Sciences/Key Laboratory of Crop and Animal Integrated Farming, Ministry of Agriculture and Rural Affairs, Nanjing 210014, China;2.School of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang 212000, China)
关键词:
黑水虻; 抗菌肽; 抗生素降解; 粪便资源化利用
Keywords:
Hermetia illucens; antimicrobial peptides; antibiotic degradation; manure resource utilization
分类号:
X174
DOI:
doi:10.3969/j.issn.1000-4440.2026.03.022
文献标志码:
A
摘要:
随着畜禽规模化养殖的迅速发展,动物粪便中排放的抗生素引发了一系列环境问题。黑水虻幼虫凭借其独特的肠道微生物组成,不仅可降解抗生素,还能将畜禽粪便转化为自身的蛋白质等。黑水虻虫体中富含的抗菌肽已被证实具有广谱抗菌和免疫调节功能。本文首先阐述了动物粪便中抗生素对环境的危害,随后分别从黑水虻降解粪便中抗生素、黑水虻抗菌肽替代抗生素这两个作用机制展开分析,探讨构建黑水虻幼虫降解粪便中残留的抗生素与黑水虻抗菌肽替代抗生素循环系统的可行性,为利用黑水虻幼虫处理畜禽粪便并实现资源转化提供新思路。
Abstract:
With the rapid development of large-scale livestock and poultry farming, antibiotics discharged in animal manure have caused a series of environmental problems. Hermetia illucens larvae, relying on their unique intestinal microbial composition, can not only degrade antibiotics but also convert livestock manure into valuable resources like proteins. The antimicrobial peptides rich in Hermetia illucens have been proved to have broad-spectrum antibacterial and immunomodulatory functions. This paper first describes the environmental hazards posed by antibiotics in animal manure. It then analyzes two key mechanisms: the degradation of antibiotics in manure by Hermetia illucens larvae, and the potential replacement of conventional antibiotics using antimicrobial peptides derived from Hermetia illucens. Furthermore, the feasibility of constructing an integrated system that couples antibiotic degradation with antibiotic substitution is discussed. This work provides new insights for utilizing Hermetia illucens larvae to treat livestock and poultry manure while achieving resource recovery.

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备注/Memo

备注/Memo:
收稿日期：2025-04-10基金项目：国家重点研发计划项目(2023YFD17020034)；江苏省农业科技自主创新基金项目[CX(23)2006]作者简介：祁杰(2000-),男,江苏盐城人,硕士研究生,主要从事农业废弃物资源化利用研究。(E-mail)15861933417@163.com通讯作者：王莉,(E-mail)xhwangli@jaas.ac.cn
更新日期/Last Update: 2026-04-17