[1]贾芮,裴娅敏,邓佳杰,等.复配了其他药食同源植物粉的葛根全粉制品的抗氧化功效评价及抗衰老作用[J].江苏农业学报,2026,42(04):817-825.[doi:doi:10.3969/j.issn.1000-4440.2026.04.018]
　JIA Rui,PEI Yamin,DENG Jiajie,et al.Evaluation of the antioxidant efficacy and anti-aging effects of Pueraria lobata whole powder products blended with other medicine-food homologous plant powders[J].,2026,42(04):817-825.[doi:doi:10.3969/j.issn.1000-4440.2026.04.018]
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复配了其他药食同源植物粉的葛根全粉制品的抗氧化功效评价及抗衰老作用()

江苏农业学报[ISSN:1006-6977/CN:61-1281/TN]

卷:
42
期数:
2026年04期
页码:
817-825
栏目:
加工贮藏·质量安全
出版日期:
2026-04-30

文章信息/Info

Title:
Evaluation of the antioxidant efficacy and anti-aging effects of Pueraria lobata whole powder products blended with other medicine-food homologous plant powders
作者:
贾芮1; 裴娅敏1; 邓佳杰1; 岳子杰1; 韩娅红1; 2; 艾有伟1; 2; 侯温甫1; 2; 3
(1.武汉轻工大学食品科学与工程学院,湖北武汉430023；2.农产品加工与转化湖北省重点实验室,湖北武汉430023；3.湖北省荆楚特色食品产业技术研究院,湖北荆州430006)
Author(s):
JIA Rui1; PEI Yamin1; DENG Jiajie1; YUE Zijie1; HAN Yahong1; 2; AI Youwei1; 2; HOU Wenfu1; 2; 3
(1.School of Food Science and Engineering, Wuhan Polytechnic University, Wuhan 430023, China;2.Hubei Key Laboratory for Processing and Transformation of Agricultural Products, Wuhan 430023, China;3.Hubei Industrial Technology Research Institute of Jingchu Special Foods, Jingzhou 430006, China)
关键词:
药食同源植物; 葛根; 抗氧化活性; 抗衰老
Keywords:
medicine-food homologous plants; Pueraria lobata; antioxidant activity; anti-aging
分类号:
S828
DOI:
doi:10.3969/j.issn.1000-4440.2026.04.018
文献标志码:
A
摘要:
为探究复配了其他药食同源植物粉的葛根全粉制品的体内外抗氧化活性及抗衰老功效,本研究基于网络药理学筛选出了葛根、甘草、马齿苋、金银花、菊花等药食同源植物,用葛根全粉与其他药食同源植物粉复配加工成复配了其他药食同源植物粉的葛根全粉制品(LPH1、LPH2)。以自由基清除率为评价指标,测定其体外抗氧化活性；并探究不同剂量(12.5%、25.0%、50.0%)的复配了其他药食同源植物粉的葛根全粉制品对果蝇存活时间、攀爬能力、体内抗氧化酶活性及氧化应激耐受能力的影响。结果表明,LPH1处理与LPH2处理对DPPH自由基、ABTS·+的清除率均显著高于葛根全粉原料对照(CK)(P＜0.05)。果蝇活体试验结果显示,25%为复配了其他药食同源植物粉的葛根全粉制品最优添加剂量,与对照相比，此剂量下LPH1处理、LPH2处理果蝇的平均寿命分别显著延长25.84%和26.41%；且在H2O2与百草枯氧化应激模型中,果蝇的存活时间均得到显著延长(P＜0.05)。综上,复配了其他药食同源植物粉的葛根全粉制品可有效提升果蝇体内外抗氧化活性、延缓其衰老进程,本研究结果可为新型葛根全粉制品研发提供理论依据。
Abstract:
To investigate the in vitro and in vivo antioxidant activity and anti-aging effects of Pueraria lobata whole powder products blended with other medicine-food homologous plant powders, this study screened medicine-food homologous plants, including kudzu root (Pueraria lobata), licorice (Glycyrrhiza uralensis), purslane (Portulaca oleracea), honeysuckle (Lonicera japonica), and chrysanthemum (Chrysanthemum morifolium), based on network pharmacology. These plants were processed with kudzu root whole powder to formulate the kudzu root whole powder products blended with other medicine-food homologous plant powders (designated as LPH1 and LPH2). Using free radical scavenging rate as the evaluation index, the in vitro antioxidant activity of the products was determined. Furthermore, the effects of different doses (12.5%, 25.0%, and 50.0%) of the kudzu root whole powder products blended with other medicine-food homologous plant powders on the survival time, climbing ability, in vivo antioxidant enzyme activities, and oxidative stress tolerance of Drosophila melanogaster were investigated. The results showed that the scavenging rates of DPPH and ABTS·+ radicals in both LPH1 and LPH2 treatments were significantly higher than those in control (CK) (P<0.05). The results of the in vivo Drosophila melanogaster assay indicated that 25% was the optimal concentration of the kudzu root whole powder products blended with other medicine-food homologous plant powders. At this concentration, compared with the control, the mean lifespans of Drosophila melanogaster in LPH1 and LPH2 treatments were significantly extended by 25.84% and 26.41%, respectively. In the H2O2 and paraquat-induced oxidative stress models, the survival time of Drosophila melanogaster was significantly extended (P < 0.05). In conclusion, the kudzu root whole powder products blended with other medicine-food homologous plant powders effectively enhanced the in vitro and in vivo antioxidant activity of Drosophila melanogaster and delayed their aging process. These findings of this study provide a theoretical basis for the development of novel kudzu root whole powder products.

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备注/Memo

备注/Memo:
收稿日期:2025-04-20基金项目:湖北省重点研发计划项目(2023BBB143)；校企研发项目(whpu-2022-j341)作者简介:贾芮(2000-),女,河南平顶山人,硕士研究生,研究方向为食品营养。(E-mail)ijiaruii@163.com通讯作者:侯温甫,(E-mail)houwenfu@whpu.edu.cn
更新日期/Last Update: 2026-05-11